Abstract: Aiming at the characteristics of the variety and uneven distribution of copper minerals in Jiama mining area, and the large differences in the properties of various mines, this paper conducts a test study on the selectability of various mines based on the study of ore technological mineralogy. Combining the various mines in actual production, a small-scale optimization test and production practice of reasonable ore blending of the selected ore from the concentrator have been carried out. Through the optimization of reasonable ore blending schemes, the clever use of sodium sulfide in grinding, and rapid flotation and other technical measures, the industrial production practice for 27 consecutive days has obtained copper grades of 21.90%, gold grades of 8.04 g/t, and silver grades of 447.04 g/ t, the copper recovery rate is 91.75%, the gold recovery rate is 67.63%, and the silver recovery rate is 66.12%. Compared with the cumulative annual technical indicators before reasonable ore blending and process technology optimization, the copper, gold and silver recovery rates are increased by 1.85%, 2.27%, 3.17%, respectively Percentage points. The efficient and comprehensive utilization of mineral resources has been realized, and significant economic and social benefits have been achieved.