Abstract: The effects and mechanism of four organic low molecular regulators tannic acid, oxalic acid, tartaric acid and citric acid on dispersion behavior of fine lepidolite were studied. Turbidity and apparent particle size test results showed that the four regulators were all beneficial to the enhanced dispersion of micro-grained lepidolite particles, and the dispersion ability of citric acid and tannic acid on lepidolite was stronger than oxalic acid and tartaric acid. The Zeta potential test showed that at the action of the regulator, the surface electronegativity of lepidolite was stronger, which increased the electrostatic repulsion force between the particles of lepidolite, and was beneficial to the dispersion of mineral particles. The EDLVO theoretical calculation showed that the total interaction energy between lepidolite particles was positive, and the interparticle force was repulsive, which was consistent with the turbidity and apparent particle size test results.