Abstract: Objective In order to conduct comprehensive utilization research on the weathering crust type vanadium-titanium magnetite in the Panxi Area, and ensure the sustainable development of vanadium-titanium iron resources in China, Method this study is based on the analysis methods of process mineralogy, investigating the chemical composition and mineral composition of the weathered crust vanadium-titanium magnetite ore in Panxi Region. In addition, a series of iron separation process experiments were conducted on the pyroxenite-type and gabbro-type weathered run-of-mine ores, including ‘dry throwing preselection-staged-grinding and staged-dressing-fine-grinding and deep-processing’. Result&Conclusion Ultimately, high-quality vanadium-titanium iron concentrates were obtained, with a TFe grade of 58.35% and a TFe recovery of 72.27% for the pyroxenite-type iron concentrate II, as well as a TFe grade of 58.13% and a TFe recovery of 33.70% for the gabbro-type iron concentrate II, achieving comprehensive recovery of high-quality vanadium-titanium iron concentrates.