Abstract: Organophosphine compounds have broad application prospects in industrial production and daily life. Their flexible polar and nonpolar groups make them have adjustable properties. There are many kinds of organic phosphine compounds and their derivatives, and their physical and chemical properties are also different, which makes organic phosphine compounds more and more widely used in production and life, especially in beneficiation and metallurgy. This paper lists some organic phosphine agents that have obtained good data in laboratory test or excellent performance in industrial application, and some representative phosphorus compound beneficiation and metallurgy reagents. Referring to some current research results and combined with production practice, this paper makes a specific classification research on them, and looks forward to their future development and application trend.