Abstract: In this study, a comparison of traditional cationic collector dodecylamine (DDA) and miscible DDA-Kerosene to the flotation performance of Jianshan ore was discussed based on the concept of reagent combination that kerosene was used as the auxiliary collector and partly replaced expensive DDA. To explore the relationship between DDA-Kerosene composition and mineral flotation performance on the reverse flotation of Jianshan ore, the characteristics of the flotation product were analyzed. The results showed that the floatability of the floating material increased with the DDA consumption increased. Specifically, during the flotation process, the fine quartz (-0.074 mm fraction) would selectively float with DDA-Kerosene. The results showed that the optimal ratio of dodecylamine was 40%, and kerosene had the most obvious effect. The addition of kerosene significantly increased the recovery of fine -0.038 mm quartz. Through the closed-circuit process test, using dodecylamine and kerosene as the collector, the iron concentrate with TFe grade of 68.57% recovery rate of 96.72% can be obtained. DDA-Kerosene with the characteristic of better selectivity and economy had a good application value in the future.