Abstract: The CaF₂ content of a quartz fluorite ore is 45.684%. Through beneficiation test, the technological process and reagent system are determined, and the relevant technological parameters and technical indexes are provided. The grinding fineness is -0.074 mm, accounting for 90%. With sodium carbonate as regulator, JK-3 and sodium silicate as combined inhibitor, YP-2 as collector, the closed-circuit process of one roughing, five refining and one scavenging, separate flotation of cleaning I tailings and scavenging I concentrate and integrated return of middling is adopted. The CaF₂ grade of concentrate is 97.682%, and the recovery is 91.87%. The test results show that the main valuable mineral fluorite in the ore has been fully recovered, the product quality is high, and the index is ideal, which provides a scientific basis for mineral processing design.