Abstract: This is an essay in the field of mineral processing engineering. Extraction of the vanadium titano-magnetite ore deposits in the Panxi Region, the biggest vanadium titano-magnetite mineral resource base, results in the production of a significant volume of tailings. The tailings have a high recovery potential of the strategic mineral resources (eg.,Vi, Ti, Fe, Co, Cu, Ni, P, and Sc). Based on the process mineralogy study, we determine the comprehensive utilization technology flowsheet and conduct a systematic recovery test of tailing samples from the Hongge mine in the Panxi Region. By the process of (1) flotation of sulfur, (2) low-intensity magnetic separation of iron, (3) high-intensity magnetic separation and flotation of titanium, (4) flotation of Phosphorous, we obtain the sulfur-cobalt concentrate (Co 0.175%), the iron concentrate (TFe 56.57%), the titanium concentrate (TiO₂ 45.97%) and phosphorous concentrate (P₂O₅ 31.73%). These results show that the systematic recovery test of tailings can reduce the production of a volume of tailings with significant economic and social benefits.