Abstract: The experimental research on leaching V2O5 by palletizing roasting and low acid was carried on a stone coach vanadium ore.The results show when the vanadium ore is pretreated under the condition of the grinding fineness of 75% passing 200 mesh,the concentration of sulfuric acid is 4%,the ration of liquid to solid is 2,the leaching rate of V2O5 can reach 88.15% under the normal atmospheric temperature.