Abstract: Content of MgO in Jinchuan copper-nickel sulfide ore is high, mainly serpentine. The production quota show that the content of MgO was fluctuates greatly in concentrate and exceeds the standard seriously, and the metal grade is high in tailings and the metal loss is large under the current technological process, which seriously affects the economic benefits of the concentrator. In order to improve the production target, the existing process flow was reformed on the basis of process investigation. The production results show that the content of MgO in high grade concentrate is less than 6.8%, the nickel recovery rate is increased to more than 87%, and the copper recovery rate is increased to about 79% after technical transformation. The concentrate quality and metal recovery rate are greatly improved, which brings good economic benefits to the concentrator.